Protein Details: Glutamate receptor 2.8

Protein ID

ICDB_Pro_1462

Protein Name

Glutamate receptor 2.8

Gene Name

GLR2.8; GLUR9; At2g29110; T9I4.19

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

947 amino acids

AlphaFoldDB

AF-Q9C5V5-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

Sequence

MNPKKNNNTFLSYFVCLFLLLEVGLGQNQISEIKVGVVLDLNTTFSKICLTSINLALSDFYKDHPNYRTRLALHVRDSMKDTVQASAAALDLIQNEQVSAIIGPIDSMQAKFMIKLANKTQVPTISFSATSPLLTSIKSDYFVRGTIDDSYQVKAIAAIFESFGWRSVVAIYVDNELGEGIMPYLFDALQDVQVDRSVIPSEANDDQILKELYKLMTRQTRVFVVHMASRLASRIFEKATEIGMMEEGYVWLMTNGMTHMMRHIHHGRSLNTIDGVLGVRSHVPKSKGLEDFRLRWKRNFKKENPWLRDDLSIFGLWAYDSTTALAMAVEKTNISSFPYNNASGSSNNMTDLGTLHVSRYGPSLLEALSEIRFNGLAGRFNLIDRQLESPKFEIINFVGNEERIVGFWTPSNGLVNVNSNKTTSFTGERFGPLIWPGKSTIVPKGWEIPTNGKKIKVGVPVKKGFFNFVEVITDPITNITTPKGYAIDIFEAALKKLPYSVIPQYYRFESPDDDYDDLVYKVDNGTLDAVVGDVTITAYRSLYADFTLPYTESGVSMMVPVRDNENKNTWVFLKPWGLDLWVTTACFFVLIGFVVWLFEHRVNTDFRGPPHHQIGTSFWFSFSTMVFAHREKVVSNLARFVVVVWCFVVLVLTQSYTANLTSFLTVQRFQPAAINVKDLIKNGDYVGYQHGAFVKDFLIKEGFNVSKLKPFGSSEECHALLSNGSISAAFDEVAYLRAILSQYCSKYAIVEPTFKTAGFGFAFPRNSPLTGDVSKAILNVTQGDEMQHIENKWFMKQNDCPDPKTALSSNRLSLRSFWGLFLIAGIASFLALLIFVFLFLYENRHTLCDDSEDSIWRKLTSLFRNFDEKDIKSHTFKSSAVHHVSSPMTQYIPSPSTLQIAPRPHSPSQDRAFELRRVSFTPNEERLTTQTIHFEDEESDIECVVEQ

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in leaves

DOI ID

10.1126/science.292.5521.1486b; 10.1038/45471; 10.1111/tpj.13415; 10.1093/oxfordjournals.molbev.a004165

RefSeq

NP_180475.2